Activate Russian CD Key

Yes but it's improbable

Steam no longer bans accounts anyway, they now "perma-lock" them, meaning no trading, no purchases, no activating new games, but still access to all games.

and yes, you can get your account locked if you use a VPN, it's all in their TOS.

You can activate the game, but it may be region locked.
So you can't run it if lock is applied.

btw, what game do you want to activate?

ask russia friend to activate is safer

yes

One line answer: Don't do it.

If you want cheap games, buy from traders on SteamTrade.