I think I read somewhere a few dozen decades ago that every combination of characters was able to get to the end, but some actions with the wrong character might bring you to a dead end. Fuzzy memories.
Some fans have made a remake with DOTT Remake style graphics. It's free, sporting a different name. Might be worth a look.
https://www.night-of-the-meteor.de/en/
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There is nothing downloadable, this is though: https://www.maniac-mansion-mania.com/index.php/de/spiele/fan-adventures/116-maniac-manison-deluxe-14.html
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"We’ve all witnessed the incredible originality of Ron Gilbert and Gary Winnick in their creations, from their clever scripts to their distinctive graphics. This video game is a tribute to them and a gift of nostalgia for all their fans."
Kickstarter.
Trailer.
Steam page.
Demo.
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