Looking for games with choices

The Witcher.

The Witcher 2 and 1 :p (RPG)

Lots of RPGs fit that description. Vampire: The Masquerade Bloodlines, pretty much every BioWare game (Mass Effect, KotOR, Dragon Age, etc), Alpha Protocol, Bastion has a bit of it, etc.

Outside of RPGs, Spec Ops: The Line comes to mind, and The Stanley Parable certainly allows you to make lots of choices.

Alpha Protocol if you're into James Bond and Jack Bauer stuff.

Mass Effect Series (I know.. EA hate, blah blah blah) but honestly the whole series is really quite excellent. If you are really hung up about the multiple endings thing for ME3.. but a cheap dlc that gives you some options.

Fallout: New Vegas, Dragon age: Origins, Dishonored, Stalker Call of Pripyat. Pretty much any good strategy is made of choices: Civilization 5, Napoleon: Total war, etc

Walking Dead is that what u need!

Fallout 3 (though New Vegas is much more dynamic), Fallout New Vegas, Deus Ex GoTY (original), Deus Ex: Invisible War, Deus Ex: Human Revolution (Director's Cut is 100000% better), The Elder Scrolls games to a lesser extent, Papers Please, XCOM games (Enemy Unknown/Within, The Bureau, and the original pack) and the Stanley Parable

The Walking Dead and The Wolf Among Us from Telltale, of course. Plus this year their studio is collaborating with Gearbox to make a game about Borderlands, so they should have even more great games like that in the near future.

The Stanley Parable.

Anything by Quantum Dream. Heavy Rain and Beyond Two Souls are limited to console, but Indigo Prophecy (Fahrenheit) is on the PC. In my opinion, this gaming company is one of the best at that type of mechanic.

FTL: Faster Than Light

Star Wars: Knights of the Old Republic

Star Wars: Knights of the Old Republic II

I know it's been said, but in my opinion Fallout: New Vegas has the most significant choices of any game I've ever played. It's nice because they aren't the typical Good/Bad choices that most games leave you with. Lots of fun gray areas to toy around with.

Easy second choice would be Dragon Age: Origins/Awakenings. DA:O had a couple choices that I had to stop playing for a few hours to toil over in my head. Pretty awesome writing. My only issue here is that I had some alternative options (very valid ones) in my head that the game didn't offer.

Bastion

ducks It does have choice and alternative endings!

Strange, I thought walking dead is just a garbage where it doesn't matter what you chose.

Star Wars KOTOR

The worst part of this question is all the answers making me want to reinstall a dozen great games. Good luck! :)

Old adventure and RPG sometimes have that. Ot at least that your dialogue options can influence how a characters responds/feels about you (kinda like ME).

The Laura Bow games were free roam, but pretty hard, because time would pass while you were wandering around and you could miss clues easily. I Have No Mouth But I Must Scream, Saints Row 3, Cry of Fear, Silent Hill games, The Cat Lady, Japanese visual novels (TYPE-Moon games, etc.), E.Y.E: Divine Cybermancy, Persona, Catherine, Fallout, Bioshock, Mermaid Swamp, InFamous, The Path, etc.

All of these have multiple endings, but at least half of them do not have dialogue choices. Some do have "action" choices; if you do or don't do something, can have a impact as well.

Try looking at Expeditions: Conquistador, too. It has a branching storyline, plus it's an awesome historical strategy-RPG set in a time period that isn't covered much by games.

witcher 1, witcher 2(become another game for who you help) fallout 1,2,3, walking dead(tell tale), dragn age, wolf among us and a lot more just keep looking.

Fahrenheit comes to my mind, kinda old but definitely an awesome game, had lots of choices and endings

Another recommendation for Alpha Protocol. You can play as the world's worst spy, the world's best spy, a horrible psychopath monster, a sociopath who only pretends to care about others, a bumbling fool that makes every single mistake and you can't understand why anyone would let him be a spy, and more and the dialogue options mean each of those will be unique story experiences.

Telltale Games
the Witcher series
Mass Effect
Dragon Age Origins
Fallout 3 + New Vegas
Fable (sort of)
the ElderScroll series
Bioshock (sort of)
Agarest: Generations of War
Analogue a Hate Story + Analogue Plus
Cherry Tree High Comedy Club
Divinity II
Dungeon Siege series (sort of)
Kingdoms of Amalur Reckoning (sort of)
Star Wars Knights of the Old Republic + Star Wars Knights of the Old Republic 2
Neverwinter Nights + Neverwinter Nights 2

That's all I've got.