Witcher 3 Wild BSOD's

0x116 would indicate that your video drivers are at fault. Try to completely uninstall them, removing as many traces of them as you can find from your computer, and then reinstall them.

If that does not work, try some slightly older drivers (say half a year old drivers) and see if those work better.

So you don't even see the windows logo or you can log into windows (tried safe mode)?

If you can't even see anything on your screen, remove the cmos battery and put it in again, and there should be some jumpers next to it, try switching it.

My best guess , the problem is your OS. I got my first BSOD after 1.5 year 2 days ago, but that was probably because of mods overload for my Risen 1 game , but I have 16 GB of Ram so it is hard for my to have BSOD.
What Windows do you have ?

Try deleting the game's configuration files here.

If you have Windows 7 , it seem this error is related with your GPU drivers you can try this fix here : https://www.youtube.com/watch?v=vPt78weVKac :D !

Only happens with Witcher 3?
Windows x64? Original/unmodded?
Power supply? Motherboard?
Is it Prime95/3DMark stable?

Have you checked the card in windows setup > device manager that it does work properly?
And what date do the drivers say.

update amd drivers!

"421110" The Witcher® 3: Wild Hunt - Corruption may be observed when AA is enabled in AMD Crossfire™ mode"

You looked into that?

http://support.amd.com/en-us/kb-articles/Pages/Optimizing-The-Witcher-3.aspx

Don't buy AMD. Problem solved.

this sounds like a weak power supply to me what brand and how many watts is your power supply? im guessing your power supply is not powerful enough to power your system now after your upgrades,almost all BSOD are from bad ram or to weak of a psu for your system and were your ram is new i would guess its your psu now specially with a new GPU thats draws more power as well as more ram. your 5850 used about 130 watts your new 5970 can draw up to 300 watts you should have about a 700watt power supply minimum for this card.

also here is a tool that will let you read you BSOD history to help see whats causing the crash http://www.nirsoft.net/utils/blue_screen_view.html

what is your cpu, if it is a low core cpu,it is possible that your cpu is in fault.

some game cannot run on single core or even on a double core cpu, you need at least 4 core and + (you need to have 4 core un-parked too)

the minimum core is 4 so it might have high chance that you cannot run it with less than 4 core

BSOD came when some of the hardware is not working properly. try reinstalling your graphics driver. remove your hardware and attach it again. and try again

I have a 7 years old Pc with 4 years old video card.
I can run it with little freezes

Intel dual core 3. GHZ
4GB Ram
Nvidea 660 GTX

Ever looked at the mimimum System requirements of the game (yeah i know, games could also work with older/weaker hardware).

Graphics: Nvidia GPU GeForce GTX 660 / AMD GPU Radeon HD 7870

So if i don't confuse (or gpu namings are already at a point where they got repeated) your gpu is to weak for it.

Make sure the ram is actually ok first; run MemTest+ from a USB stick.

If the ram is ok then completely remove the videocard drivers (via uninstall and maybe even via a dedicated cleaner program). Then restart Windows and let it detect the videocard and install drivers for it. Test if the game works and then decide if you want to download the latest drivers from the videocard manufacturer's website.

Seems like youve put a lot of time into this already.
Ive been in similar situations and at some point said fuck it, I´m doing a clean OS instal. It helped every single time.

And if youre gonna do that. Grab Windows 10. Why? Check here.

Sometimes a fresh start is all you need, especially when you changed some hardware.

Maybe there's problem with ur hard disk, Try checking it with Hard Disk Sentinel, This software will give info about ur hard disk is on good or bad condition. I had this type of problem in the past and I figured out it was my hdd causing those bsod (bad sector).
Btw can u run other graphics hungry games without bsod or without any issues?

I didn't expect to get so many people helping me with this problem, thank you all, you are awesome

i had a similar issue last week turn out my power cord from my psu to my graphic card was melted (found it yesterday) so i looked at the requirement for the 5970 and i found that it required 2 power cord (75W 6-pin and one 150W 8-pin, if you are you using the same wire like the one on the picture(not from my pic) , it is possible that it's the problem). , it might be a cable problem (short circuit drain the psu voltage/wattage).

I was using a single power cord with 2 end and it turn out that the connector in the psu melted pretty badly and was causing a short circuit. My graphic card was running fine (until a week ago) under normal or low load but tend to crash at high load (i needed to clean my pc, to much dust ) si i was thinking that it was a heat issue. even at low load my psu had low voltage so i was thinking it was a bad reading because it is a good quality and the voltage was really stable so i never thought that the cable was the problem until i plug another heavy power card and then realise that the card was not detected like it was un plugged. well turn out it was only 1 power cable that caused all those issue.

if you have a modular psu, just try to unplug every power cord and look if they are melted/damaged. If the cable cannot be removed, the change that it is actually melted is pretty high and might be the cause of your problem. still remember that if you are using a single cable, approximately 250 watt can go through that small wire

http://s308.photobucket.com/user/BababooeyHTJ/media/WTF.png.html (cannot be inserted to this message )

Ah, Does your CPU has integrated Graphics?
If yes, go to bios, disable it. Now, go to control panel and see if Windows has installed drivers for Intel integrated graphics. IF yes, uninstall them. restart. This will work 99%.