Fanatical region-locks?

Depends on the game and your region.

best bet is to look at steamDB and the fanatical store page for the game and see if you can match up which package it is. If its a previously bundled by fanatical game you can check the SG discussion page for the older bundles to see if it was region locked in them.

Mystery bundles love to toss PRC restricted keys in them, but sometimes you get significantly locked down keys(your only guaranteed to get keys working in your region after all)