Who's Your Favorite Villain?

Gul Dukat - Star Trek: Deep Space 9

How about Zero from the Zero Escape Series (999 and Virtue's Last Reward)

Of the games I've played recenly, Bioshock 1's Andrew Ryan comes to mind (and adding bioshock 2's backstory bits helps), I love how that story ended.

Jackanapes

Not my favorite, I just think he's funny. xP

Handsome Jack! That guy is hilarious (and handsome)!

I have a few favorites - Wesker from RE, Revolver Ocelot and Vergil from DMC3.

Other than Magneto and Doctor Doom, I can't really think of any 'real' villains that I like.

For some reason Daud from Dishonored always struck me as a cool villain. My favourite movie villain is probably Emperor Palpatine from Star Wars.

My favourite video game villain <spoiler free>, while probably cliche, is <the only boss fight in Portal>. Kerrigan from Starcraft is another classic.

Kefka anyone?

Vaas. Nuff said.

The Helghast in Killzone. Throughout the game, I just can't feel I'm playing the good guy invading some other people planet killing everyone.
Or maybe there's some back story/history that I missed?

The joker(the dark knight joker)
What to say? some people just want to watch the world burn

Darth Vader.

Deadpool.

I have a couple. Both are evil, cruel, cunning with a twisted sense of humor. Aku and Mark Hamill's Joker.

Wait, Discord.

SHODAN

Dr. Evil

Talia Al Ghul, because she has the best ass ever.

Joker from the comics and games (although Jack Nicholson's performance was great :D), Handsome Jack from Boarderlands 2 is charming, funny and a complete bastard, Andrew Ryan from Bioshock (Rapture is a great novel and worth a read) because <possible spoilers>, Seska from Star Trek Voyager because <spoilers>, Vaas from Far Cry 3 <spoilers>, Dukat from Star Trek DS9, Negan from The Walking Dead comics <spoilers>, Saren Arterius from Mass Effect, and Callisto from Xena Warrior Princes. Probably lots more but these are the first few that spring to mind :)

The best Villains are always the ones that when they explain their reasons for doing all the evil things that they do you just kind of get it. You understand that why they did it and you can't completely rule out that you wouldn't have done the same yourself. It's this nice mix of logic and emotion that you so very rarely see anymore.

Scorpius from the Farscape series was a great example of this, he spends half the series being just plain evil, even looking like something out of a cartoon, then when he finally gives away his backstory a small part of you start rooting for him to win.

Games very rarely get this right usually opting for the cartoonish want to destroy/own the world. In recent memory they tried it with Loghain in DAO but unfortunately failed by not explaining it properly.

this guy

Shodan from System shock

The Red Guy!