Brutal Legend.

Darksiders, Deus Ex Human Revolution and Gravity Rush.

1: Civilization IV

2: Twin Bee

3: Zero Wing

Not ranked because it isn't the games theme (otherwise it would have clearly won here): F-Zero - Big Blue
Unranked due to being the video game national anthem: If you didn't knew what it was gonna be before clicking...

Deus Ex HR <--- the best imo.

The Elder Scrolls III Morrowind

Mafia 1

There are many more epic ones like Max Payne, Uncharted, Skyrim etc.

Shadow of the Colossus.

Serious sam SE last mission soundtrack

Ys.

Guild Wars

Neverhood and Skullmonkeys. There's nothing more epic than that.

assassin's creed II - Ezio's Family I believe it's called

Tribes Ascend when the match ends.

1 - civ 4

2 - borderlands 1,2 intro

3 - saints row 3 intro

The Binding of Isaac
Listen to all the songs, they're amazing. The video above starts at my favourite one.

Zelda series

I wonder why noone mentioned this before.

Just love this one from Darksiders 2 !

Also love this one.

C&C Red Alert 3 - Hell March 3

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• Morrowind
• Metroid Prime
• Fable
• Halo
• Trine
• Killer Instinct
• Duke Nukem 3D
• One Must Fall 2097
• Doom
• Full Throttle
• Donkey Kong Country
• Dragon Age
• To the Moon

Off the top of my head :D

Anything Jeremy Soule has worked on, minus Skyrimjob.

I personally love his early work, like Dungeon Siege. This one in particular.

Shadow of the Colossus

halo combat evolved , skyrim , mirror's edge , wow clasic/tbc/wotlk/cata/mist

From Witcher series, I love that soundtrack!
http://www.youtube.com/watch?v=dCk7wpk5Fys
http://www.youtube.com/watch?v=vfCzTcydsX0

1-god of war 2 ( rage of sparta , the end begins , poseidon wrath ...)
2-Red alert (hell march 1,2,3 , soviet march ... )
3-idk .

• Assassins Creed since AC II
• Rayman Legends
• Guild Wars 2
• Legend of Zelda

While it's not the theme for it, Knights of the Old Republic 2 (to be honest, I'm not entirely sure what the theme is. The standard Star Wars fanfare?) this is the theme as I see it, as it what I always remember when I think of the game, both in music and one of the most melancholy scenes.