Saddest Video Game Moment Ever?

When Professor Pester came into my garden and destroyed my white Tigermisu. A sad day for Pinata's everywhere...

the end of kafei's quest in majora's mask.

Shenmue 2 cliffhanger

Ending of Bastion is sad no matter what you choose.

Binding of Isaac's 13th ending is damn sad as well, if you understand Blue Baby.

Ending of Oblivion is quite bittersweet and honestly pretty damn sad.

The deaths in Borderlands 2 were damn sad.

Red Dead Redemption's ending of course

Hit a mine in a Minesweeper.

star craft
SPOILER
when you must kill fenix..

also the ending of star wars republic commando

Ending of L.A Noire
Darkness 2 was sad overall xD
Mirrors Edge ending for some reason...The song makes it more sad in the end and the scene where you zoom out to the city view <3
Homefront starting too when they kill the childs parents etc made me sad :\

Gremio in Suikoden. Won't give spoilers (despite the game being so old) but if you've played it you know. That game had a lot of sad moments though.

A retroactive one for those who played To The Moon: "What else?"

Since To The Moon has obviously been said a million times, I'm going to go with Final Fantasy X.

spoilers

To find out that your main character was a dream all along, seeing Yuna's face as she realises and tries to run for one last hug, only to fall through his incorporeal form. The last whisper "I love you..." -- that was friggin' epic.

When Liara put the name of Sheppard in the Memorial of Normandy - Mass Effect 3

Borderlands 2 - 'Saving' Angel.

Apart from what everybody said before, a very sad moment was the true ending of Mad Father. It's a little freeware indie game. You guys should give it a try :)

I'm surprised that nobody said the ending to MGS4. But my saddest moment is Hinawa's death from Mother 3

I will always remember this cutscene from MGS: http://www.youtube.com/watch?v=Gi3zU7o3Gks

Going back to the metal gear snow place (forgot the place name) while in metal gear 4.

When 'Ryan' sinks Fontaine's bathysphere with his family inside. D:

Edit: Saddest moment ever was when my dog was blown up by a creeper on minecraft.

Max Payne 2 ending (detective mode)

No returns/refunds when buying a bad game.

The walking dead and Parts of borderlands 2

Fallout 2 ending when Elder dies

When people believed Sony's lies that the Playstation 2 was as powerful as they said.