It slightly changes the color palette that you see. It may be less fatiguing, but hell, 100$? There is no magic in it, just coloured lense with filters. People report comfort issues, some say it just doesn't work on them. I would advise some testing before buying.
I didn't like the fact they made white look yellowish so I ended up not buying them. White light is eyestraining, sure, but I enjoy it anyway.
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If computer use irritates your eyes then there are other things you need to consider first.
-If you have a LED monitor then you might be sensitive to PWM. There are LED monitors that do not use it. A monitor upgrade may be more expensive than those glasses but the glasses can't help you with PWM sensitivity.
-It's possible your monitor is too bright. Most people overestimate how bright a monitor needs to be and have theirs set at 100% which can be up to 3 times brighter than a CRT could do and very bad for your eyes.
-It's possible your monitor is poorly calibrated. A proper calibration requires a colorimeter/spectrometer and is probably not worth the cost to you. You can still do basic adjustments with this site that can help quite a lot.
-There is a flexible program out there that can adjust the colours of your monitor to something more comfortable.
-Other cause of tiredness are: you may be sitting too close to the monitor, the monitor may suffer from crosshatching, your stance on the desk may be poor, room lighting may cause glare especially if the monitor has a glossy screen, the monitor may have a very hazy coating.
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In addition, look at the lighting behind your monitor. One of the biggest issues is the contrast of the brightness of your screen and the space around it. Make sure that it's not extremely dark behind your screen as your eyes will try to adjust to bright/dark very quickly over and over again and this can contribute to the headaches.
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+1000000, it does the exact same thing and they recently added features to turn down brightness as well as intensity so you ruin your eyes even less at night (i believe its automatically set to alt+numpad3 to lower it and alt+numpad9 to increase it if you make it too low, although it automatically does that anyway when day comes)
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99 dollars? Holy crap, that's an obvious rip-off. You could probably find a better solution somewhere with a different pair, or simply change the color pallete in your screen options.
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