Substitute up to two characters in a game's title to make a new game title

Deuce Ex -- a card game based on the Deus Ex universe. Wanna pit JC Denton vs. Alex D? You can now! (without forgetting current poster kid Adam Jensen)

MooD - a first-person shooter where you kill of hordes of your own inner demons, brought forth by your current mental state.

Super Beat Box - The voice contolled, rythm based runner game! Make your character move with your mad beatboxing skills (microphone required)

Master of Onion 2 - the classic 4x kitchen management game.

Dead Raisin - You're trapped in a green-grocery store. Fight off the hordes of undead fruit, and the occasional psycho vegetable.

Rapers, Please - NSFW.
Garry's Rod - Yet another NSFW game.
Mad Wax - A game about bees & stuff.
Cook, Serve, Religious! - A game about managing a religious restaurant.
To The Moo - A game about a man wishing to get to a certain cow.
Tomb Maiden - A game about some undead woman.
War Blunder - A game about losing a war.
Starhound - You like hounds, don't you?
Mortar Wombat - A game about weird people using wombats as munition.
Mantischamber - Go into a chamber full of mantises.
Beardbuddy: Tale of the Guardians - Your buddy is growing a beard! You must be a guardian of well-shaved faces and change his mind.
420 Labours of Hercules - Memes.

Sing of Dragon Piss

You are a bard who follows Dragons and compose songs about their... well... bathroom moments.

Poor Lickers

A quest involving discovering how homeless people taste.

Womb Raider - Where Lora Kroft raides long forgotten wombs
Final Fantasy XXX - Totally not the pornhub version. Its the next game in the series after Final Fantasy XXIX.
Left 4 Head - I wont comment
Carl on Duty: Black Cops- I saw this on a gaming page once. Technically 3 but nevertheless sharing.
Dead Spice- All the spices are coming for you.
Wagon Age: Origins- How the age of steam wagons started.
Car Fry- A game about making delicious car fries.
Euro Luck Simulator- Try your luck now in Europe.

D4: Dork Dreams Don't Dye
This weaver simulator takes place on an monochromatic asylum where the absense of color give the patients psychic power and godly weaving abilities, the main character uses this power do uncover his wife's demise and grant her last wish "Look for some dye" so he can bring color to this world.

BayZ: all these zombies must explode. Bonus points for the most noisy and shiny booms !

The Bitcher - game about a whiny old man

Warlock - Master of the Arcade
Level your warlock in the art of subtle manipulations of reality and cheat your way to the top of the high score lists. Just beware the observers, which will give you severe debuffs.
Chaos on Demonia
Rufus is let loose to wreak havoc in the 9 rings of hell.
Tribblenauts Unlimited
Tribbles everywhere. Can you contain the pest? Gore galore.
Cattlepaths
You are a scout in training. Can you find the lost Cows?

Final Fartasy! :|

Alternatively, God of Worn

Yes they're bad but I could have made them worse. ;P

The Rhoid- it's a biggun
Violate-umm
Voyage to Fartland -pew pew
Warfart - pew pew
7 Ways to Dive - diving simulator
8BitBrony-
Absconding Zatwhore -a tale of kidnapping
Alien Breeder: Impact - these guys are rough
ARF: Survival Evolved -open world dog survival
ShitLord - collect all you can
The Shit -harass all the other players
N.U.B.E. -a game for people who never gamed before
Poop Nation -it's the currency
Slapping Dogs -make em yelp
Stinking Island -make your way through the garbage
Space Farters -it's their propulsion
Vault Crapper - must fill em up
Hasteland -infinite runner game
Whisper of a Nose -snoring simulator
Warts Revolution -eliminate all warts
Zombie Bowl-U-Mama -poor moms
ScribbleNuts Unlimited -a timed drawing game

Oh alright.
I'll throw in some more:

Shallow Warior - an FPS with minimal depth in every way. Characters don't have background or motivation, levels have goals but no narrative surrounding them, and in fact every level has the same basic structure and you only get one weapon.

Galactic Shitman - Digital Homicide's actual sequel to Galactic Hitman, taking the most common nickname and selling it off as something new. Who knows, they might turn it into a top-down shooter this time around.

Duke Pukem - Just like Duke Nukem, but with more food and/or alcohol poisoning.

Pigshock - Another FPS, with symbolism based around the image of Little Piglets that need to be saved from Big Wolves.

*Titties in Motion 2
Game that will bounce your brain out! :

*Fitman: Absolution
Get a cheat day every day!

Just a few:
Grool Nation - Billiards on slippery tables. Can you pot them all?
Lemonicon - A semi-epic quest about defeating the limey demon from Hell.
Warrior Sings: Cattles - Karaoke game based on beefy songs. Purchase DLC for country remix songs about cows.
Wacky Peels - Fruit peeling simulator.
Unreal Pournament - Left outside alone, with only a half-broken umbrella! Test your survival skills when battling heavy rain!
Slice Toad - Interactive teaching game for biology class.
Cooks Peep - Beware of the stalking cook!

The Glitcher - Epic tale about mutant created with sole purpose, to be litteraly able to glitch through enemies, leaving them defensless. (Or this could be the name of main protagonist of any Bethesda game:P )