Remove 1 letter from a game title and provide a new synopsis.

The Itcher -- Fast-twitch game where you have to scratch various body parts or be consumed by horrible skin conditions.

Meal of Honor. you eat your way through war, for honor.

Money Island

Himan: A story about an assasin who loves Adele (?) and saying hello

Silent Ill - A mysterious illness is killing everybody in a lonely town
Meal Gear Solid - Snake runs out of rations and starts eating gears
Dad Rising - After 30 years, your dad is finally promoted
BioSock - I told you it wasn't a great idea to keep your socks for a whole month...

The Sis 3: a new porn VN about... your sister.
BAD ATs: You are a kid who tried to not be vaccinated
Counter stike: MotoGP pilots fight agains the invasion of the trikes in the circuits
Iberia: a new flying simulator made in spain, wait! delayed again? ok... next lauch date: 10 dec 2034

Arming Simulator: you're the POTUS and you have to arm as many terrorists as you can without getting caught. Then you declare war on them and make it look like you are the good guy.

Rain Simulator: for those that really love to play in the rain
Tran Simulator: if you're not sure yet, but you want to know what it's like
Ark of the Ninja: you're Noah... but you're also a ninja

Ding Light: a Wow addon that lights up the screen when you "ding"
Alien Warm: keep aliens warm, because they need love too
Boderlands: something, something to do with shops?

Feel free to add better descriptions if you have some :P

Town of Sale - Story about the town worshipping lord Gaben.
Guacamelee!: old Edition - Very old edition of Guacamelee
licker Heroes - Emm... I guess this could be porn?

10% Orange Juice: You are trying to convince company to make their juice better.
Chi: Something about flying man with moustache doing wierd things using his inner peace.
Cosmic D: ...
Ekopara: Paradise where everyone is ecological.
Half Minute Ero: Peek at girls as much as you can as quickly as possible.
Oxelized: Changed into an ox, our hero explores grasslands to find a way to get rid of his curse.

DC Universe: you know what I'm sayin...

The Walking Dad - Find out what it is like to be a dad that walks.
Hurtword - Your character gets hurt if you make a spelling mistake.
Rebuild 3: Gangs of Dadsville - You have to rebuild a city after an invasion of dads.
Planetbae - Can't choose the perfect bae? Here's a planet full of them!
Plane Explorers - Have no idea what the inside of a plane looks like? Explore it here.

DEA Space - The Drug Enforcement Agency builds a rocket to find the lab where Space Cake is produced. Could the whole "The moon is made of cheese for making cheesecake" be a front for this elusive gang of munchers?

Bull: Scholarship Edition - Go to Bullworth academy, try and bag the best cow out there for mating season. The original bovine dating sim!

Castle Rashers - A voxel based building game, design your castle completely with rashers of bacon! Like Minecraft, only TASTY!

Fallout: New Vega - Traverse the wasteland as everyone's favourite Street Fighter's clawed Spanish fighter. Deathclaws all around will be jealous!

FHL: Faster Han Light - How many parsecs will it take you to cross the galaxy in the Millenium Falcon? Find out in this Star Wars rougelike!

I Have No Mouth, and I must Scram! - ARGH! YOU HAVE NO MOUTH! RUN! You've played the best, now play the rest, it's Temple Run but this time....it's mute!

MEAL SLUG - You're starving, you're an army man who for some reason is saving shirtless bearded men, you are hungry, time to eat...THE MEAL SLUG!

Super Eat Boy - You're a boy, you're not very good at most things, but you're super at eating! Dine out! Critic restaurants! Download the meal slug DLC!

There's more but these will have to do!

Ever alone - game where it counts your hours of you being alone and you can compare it to people in your friendslist about who is on the top of leaderboard.
Lender(man) - A game where you need to manage all things you lend.
Lie is hard - Simulator for experiencing consequences of "to lie" or "not to lie".
ET set radio - E.T. is trying to build a radio communication device on Earth again. It is second game in the trilogy, first was ET Racing extreme and third ET Gunner.

T.A.L.K.E.R

Numa Deluxe - An exciting, all-new gaming experience which is fun, challenging and will help you increase your overall dancing fitness!

(number removal) 1 Wheels of Steel: American Long Haul - Track across America on your unicycle.

Rain Simulator - Take control of nature and be in control of the water cycle. Don't forget to buy our other DLCs to play on various different locations plus more.

Ar Cry - You are a pirate with two hooks for hands and a splinter in your good leg...

While we're still at it, how about...

Gunpint - the drinking game with oversized shot glasses
Fallot 3 - the 3rd adventure based on Etienne-Louis Arthur Fallot, the historical French physician who specialized in cardiology

If my heat had wings :S

Alen: Isolation - Alen is all alone.
Evil Genus - Scientists pinpoint exactly what makes people evil
Left 4 Dad - Mom goes on vacation
Pi - It's just numbers
Rad Only Memories - This thing's memories are crazy awesome
Shovel Night - The story of a gravedigger
World of Go - If you stop you die

Tow of Salem - Manage your own simulated towing company on the scenic coastline of Massachusetts
Spec Ops: The Lie - You spend the entire game claiming to be the leader of a special recon team sent into a conflict zone on a secret mission, but really you've made the whole thing up.
Reaming Sarah - You know, I don't think I actually want to write this summary.

This thread is awesome. Some of these made me laugh pretty hard.
I could only think of one new title, but someone already posted it.

Mount Your Fiends : explore the clouds on the back of flying crack-addict, searching for Lucy and her diamonds
Streets of fur : visit Paris with cute animals for company
Volve : Help Gabe and his teammates hunt the horrible monster who changed a letter in his company name, or play the monster

The Hip: A game about an old divorced man trying to find love with young girls on a cruise.
AYDAY: AAAAYYYYYY
The Long Ark: Try to survive on Noah's Ark
Got Simulator: Just another simulator, you gotta get it.
Castle Rashers: One knight goes through an entire game to find some rash cream for his kingdom.

Left 4 Dad - You grown up and need to leave home... for your dad!

Person 4 - In a small town in Japan's country-side, a few teenaged persons who can summon persons called "Person" look for a person who is killing some persons.